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目的了解海南省农垦某综合医院结核病患者治疗与转归情况,分析其影响因素。为制定有效的结核病防控措施提供依据。方法搜集2010年1月1日～2012年12月31日期间在海南省农垦某综合医院治疗的2 965例结核病患者的病案资料,回顾性分析患者住院期间结核病患者的治疗转归情况和相关影响因素。结果共有2 965例结核病患者,其中肺结核2 592例(87.42%),肺外结核373例(12.58%),平均住院30d(最大值399d),每例平均费用14 183元。有合并症的853例(28.76%),其中肺部感染最多536例(占合并症62.84%)。患者平均年龄(53.88±18.53)岁,其中60岁及以上1 171例,占患者总数的39.49%。男女性别比为2.65:1。患者中农民占33.49%。共治愈234例(7.89%),好转2585例(87.18%),未愈101例(3.41%),死亡13例(0.44%),其他(主要为患者自动出院)32例(1.08%)。单因素分析显示:不同性别间差别无统计学意义(χ2=0.02,P>0.05)。不同年龄(≥60岁组与<60岁组)间差别有统计学意义(χ2=8.91,P<0.05),低年龄组治愈率高些。不同职业间差别无统计学意义(χ2=12.22,P>0.05)。有无并发症间差别有统计学意义(χ2=64.37,P<0.01)。结论年龄与合并症等是影响结核病治疗转归的主要因素,应关注老年伴有合并症的结核病患者的治疗。
Objective To understand the treatment and prognosis of tuberculosis patients in a general hospital in Hainan Province and analyze the influencing factors. To provide an effective basis for prevention and control of tuberculosis. Methods A total of 2965 cases of TB patients treated in a general hospital of Hainan Provincial Land Reclamation from January 1, 2010 to December 31, 2012 were collected. The treatment outcome and related impact of tuberculosis patients during hospitalization were retrospectively analyzed factor. Results A total of 2 965 cases of tuberculosis were found, of which 2 592 cases (87.42%) were pulmonary tuberculosis, 373 cases (12.58%) were pulmonary tuberculosis, the average hospitalization was 30 days (maximum 399 days), with an average cost of 14 183 yuan per case. There were 853 cases (28.76%) with comorbidities, of which 536 cases were pulmonary infections (accounting for 62.84% of all comorbidities). The average age of patients (53.88 ± 18.53) years, of which 1 171 aged 60 and over, accounting for 39.49% of the total number of patients. The ratio of men to women is 2.65: 1. Among the patients, 33.49% were farmers. A total of 234 cases (7.89%) were cured, 2585 cases (87.18%) were improved, 101 cases (3.41%) were unhealed, 13 (0.44%) died and 32 (1.08%) were other patients. Univariate analysis showed that there was no significant difference between different genders (χ2 = 0.02, P> 0.05). There were significant differences between different age groups (≥60 years old and <60 years old) (χ2 = 8.91, P <0.05), and the cure rate in the younger age group was higher. The difference between different occupations was not statistically significant (χ2 = 12.22, P> 0.05). There was no significant difference between the complications (χ2 = 64.37, P <0.01). Conclusions Age and comorbidity are the main factors influencing the outcome of TB treatment. The treatment of TB patients with comorbid elderly should be paid attention to.