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婴儿猝死综合征(SIDS)的死者,其颈动脉体中的度巴明(dopamine)和正肾上腺素的含量,显著高于同龄对照组婴儿,分别高出10倍和3倍。在给予度巴明时,该药会直接作用于颈动脉体而抑制呼吸,提示SIDS死者内生性儿茶酚胺(Catecholamine)含量增加,且可能影响颈动脉体的正常功能,特别是缺氧时的通气反应功能。作者在多伦多医院病理科所进行的尸体解剖中,得到18例婴儿的颈动脉体。其中13例为SIDS死者,5例为对照组。这13例均有典型临床病史,颈动脉体无显著的肉眼或镜检病变,培养或镜检亦无感染的证据,
The deceased of sudden infant death syndrome (SIDS) had significantly higher levels of dopamine and norepinephrine in the carotid body than those in their control group, 10 and 3 times higher, respectively. The drug will exert a direct effect on the carotid body to suppress respiration when given to tebumin, suggesting an increase in endogenous catecholamine levels in the deceased SIDS and may affect the normal function of the carotid body, particularly the ventilatory response during hypoxia Features. The authors obtained carotid bodies from 18 infants in autopsy conducted by the Toronto Hospital Pathology Section. Of these, 13 were SIDS dead and 5 were controls. These 13 cases have a typical clinical history, no significant carotid body or microscopic examination of lesions, culture or microscopic examination also no evidence of infection,