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目的:探讨喉癌患者不同手术方式的临床疗效及预后影响因素。方法:对68例喉癌患者临床资料进行回顾性分析,其中行喉癌全切术患者32例,行喉癌部分切除术患者36例。比较两组的3年、5年生存率,并对可能影响预后的因素进行统计学分析。结果:喉癌全切与部分切除术患者3年生存率分别为75.0%和77.8%,5年生存率分别为68.8%和72.2%,差别均无统计学意义(P>0.05);肿瘤原发部位、淋巴结转移和TNM分期是影响喉癌预后的风险因素。结论:喉功能保全性手术是治疗喉癌的理想手术方式,而肿瘤原发部位、淋巴结转移和TNM分期是影响喉癌预后的风险因素。
Objective: To investigate the clinical efficacy and prognostic factors of different surgical approaches in patients with laryngeal cancer. Methods: The clinical data of 68 patients with laryngeal carcinoma were analyzed retrospectively, including 32 cases of total laryngectomy and 36 cases of partial laryngectomy. The 3-year and 5-year survival rates of the two groups were compared, and the factors that may affect the prognosis were statistically analyzed. Results: The 3-year survival rate was 75.0% and 77.8% in patients undergoing partial or partial laryngectomy, respectively. The 5-year survival rates were 68.8% and 72.2%, respectively, with no significant difference (P> 0.05) Location, lymph node metastasis and TNM staging are risk factors affecting the prognosis of laryngeal cancer. Conclusion: Laryngeal preserving surgery is the ideal surgical treatment of laryngeal cancer, and the primary tumor site, lymph node metastasis and TNM staging are risk factors affecting the prognosis of laryngeal cancer.