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头颈部鳞癌是一种较常见的恶性肿瘤。p34cdc2及cyclinB1是调控G2/M期的重要蛋白,可以促进G2/M期转换而加速细胞周期进程。关于p34cdc2及cyclinB1与头颈部鳞癌的发生发展及预后的研究目前已相当普遍。本文就它们在头颈部鳞癌中的预测价值进行综述。
Head and neck squamous cell carcinoma is a more common malignancy. p34cdc2 and cyclinB1 are important proteins in regulating G2 / M phase, which can accelerate G2 / M phase transition and accelerate cell cycle progression. The research on the occurrence, development and prognosis of p34cdc2, cyclinB1 and head and neck squamous cell carcinoma is now quite common. This article reviews their predictive value in squamous cell carcinoma of the head and neck.