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作者分析从1969年8月至1977年2月,收治的209例小细胞支气管肿瘤患者的发病次数、部位、临床症状、诊断和治疗方法以及生存期的情况。结果如下:发病次数:209例患者中,临床诊断有中枢神经系统转移的患者是102例(49%)。85例尸检患者中,有中枢神经系统转移的55例(65%)。已有骨转移的患者,其中枢神经系统转移的发生率较高,尤其在软脑膜部位。定位:绝大多数转移均在大脑半球和小脑半球(55例患者中有83%),并且常为多发性。四分之三的患者在中枢神经系统其他部位也发现有转移。
The authors analyzed the incidence, location, clinical symptoms, diagnosis, treatment, and survival of 209 patients with small cell bronchial neoplasm admitted from August 1969 to February 1977. The results are as follows: Number of Incidences: In 209 patients, 102 patients (49%) had a clinical diagnosis of central nervous system metastasis. Of the 85 autopsy patients, there were 55 cases (65%) of central nervous system metastases. In patients with bone metastases, the incidence of metastases in the central nervous system is high, especially in the pia mater. Localization: Most metastases are in the cerebral hemisphere and cerebellar hemispheres (83% of 55 patients) and are often multiple. Three-quarters of patients also have metastases found in other parts of the central nervous system.