为评价小剂量阿斯匹林对先兆子痫发生率、出生体重、妊娠高血压、早产和胎儿生长迟缓发生率的影响,从7所医疗中心随机指定3135名孕13～27周健康妇女,每天服阿斯匹林60mg(n=1570)或安慰剂(n=1 565)。150名失访(4.8％),2 985名追访至妊娠结束。2次间隔至少4小时测收缩压140mmHg,舒张压90mmHg定为妊娠高血压。妊娠高血压+蛋白尿(≥300mg/24hr或≥2+,2次间隔至少4小时)定为先兆子痫。结果表明阿斯匹 To evaluate the impact of low-dose aspirin on the incidence of pre-eclampsia, birth weight, gestational hypertension, prematurity and fetal growth retardation, 3135 healthy women of 13 to 27 weeks of gestation were randomly assigned from seven centers each day Aspirin 60 mg (n = 1570) or placebo (n = 1 565). 150 lost to follow-up (4.8%) and 2 985 to the end of pregnancy. Two intervals at least 4 hours measured systolic blood pressure 140mmHg, diastolic blood pressure 90mmHg as pregnancy-induced hypertension. Pregnancy-induced hypertension + proteinuria (≥300 mg / 24 hr or ≥2 +, 2 intervals at least 4 hours) is defined as preeclampsia. The results show Aspirin