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早在三十年代初期,Von Euler在研究人精液和绵羊精囊提取物时,首先发现了一类可溶性的酸性脂类——前列腺素(Prostaglandin PG)。前列腺素是一组由20碳不饱和脂肪酸组成的化合物,它们的化学结构中均具有一个五碳环和二条边链,一般多采用习惯名称命名,例如根据环外双键数目分为PG_1、PG_2、PG_3三类,以及根据环上结构不同分为E、A、F、B四型。到目前为止已经发现的前列腺素有20余种,常用的有前列腺素E(PGE),前列腺素A(PGA),前列腺素I(PGI),前列腺素
As early as the early 1930s, Von Euler first discovered a class of soluble acidic lipids, prostaglandin PG, in the study of human semen and sheep seminal vesicle extracts. Prostaglandins are a group of compounds composed of 20-carbon unsaturated fatty acids. Each of them has a five-carbon ring and two side chains in its chemical structure. Generally, the prostaglandin is often named after the customary name. For example, the prostaglandin is divided into PG_1 and PG_2 , PG_3 three categories, and according to the ring structure is divided into E, A, F, B four. So far there have been more than 20 kinds of prostaglandins have been found, commonly used prostaglandin E (PGE), prostaglandin A (PGA), prostaglandin I (PGI), prostaglandin