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镍钛合金胆管内支撑架用于恶性胆管梗阻是近年出现的新疗法。本研究中16例晚期胆管瘤患者采用了镍钛合金内支撑染治疗,并与13例晚期胆管癌施行胆肠吻合内引流术进行了疗效对比。、结果:术后1周血总胆红素含量由术前的285.13±101.44μmol/L降至27.43±10.40μmol/L(P<0.01),术后2周黄疸均基本消退。术后生存时间为11.81±5.54月,无并发症出现。与胆肠吻合内引流术比较,两种治疗在减黄速度和效果以及生存期限上均无显著性差异,但在生在质量上前者明显优于后者。镍钛合金内支撑来用于治疗无法切除胆管癌较以往各种内引流术具有方法简单、创伤小、引流效果佳。并发症发生率低且符合正常生理解剖状态等优点,明显提高了患者带瘤存活时间和生存质量,是一种值得临床推广的新疗法。
Nickel titanium alloy bile duct internal support for malignant bile duct obstruction is a new therapy in recent years. In this study, 16 patients with advanced cholangiocarcinoma were treated with nitinol stenting and compared with 13 cases of advanced cholangiocarcinoma. RESULTS: Total blood bilirubin levels decreased from 285.13±101.44 μmol/L to 27.43±10.40 μmol/L (P<0.01) 1 week after surgery, and 2 weeks after operation. All basically subsided. The postoperative survival time was 11.81±5.54 months without complications. Compared with biliary-enterostomy drainage, there was no significant difference in the speed and effect of yellowing and the duration of survival between the two treatments, but the former was significantly superior to the latter in quality. Nickel-titanium alloy internal support for the treatment of unresectable bile duct cancer has a simpler method, less trauma, and better drainage effect than various internal drainage methods. The low incidence of complications and the fact that it meets the normal physiological anatomy and other advantages, significantly improved the patient’s tumor survival time and quality of life, is a new therapy worthy of clinical promotion.