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目的:探讨彩色多普勒超声检测足月妊娠孕妇左侧卧位下腔静脉、子宫动脉及胎儿脐动脉的血流动力学变化。方法:回顾分析2014年1月—2019年10月在东南大学医学院附属江阴医院就诊的73例单胎足月妊娠孕妇的超声资料。孕妇年龄20~42(29.34±5.16)岁,孕周37~40.3(39.1±1.0)周。孕妇均采用彩色多普勒超声诊断仪进行检查。观察项目:(1)比较73例孕妇平卧及左侧卧位15°时,于剑突偏右、肝静脉汇入第二肝门处测量的下腔静脉内径和血流最高流速,以及子宫动脉和脐动脉的收缩期峰值最高流速(PSV)、舒张末期流速(EDV)、搏动指数(PI)、阻力指数(RI)、PSV/EDV(S/D);(2)据超声检查时有无出现仰卧位低血压综合征(SHS)将孕妇分为有症状组和无症状组,分别比较两组孕妇平卧位、左侧卧位15°时下腔静脉内径和血流最高流速,子宫动脉、脐动脉血流动力学参数,以及孕妇的年龄、孕次、产次、孕周、体质量指数(BMI)及新生儿体质量等;(3)比较有症状组孕妇平卧位和左侧卧位15°时下腔静脉内径、血流最高流速。结果:(1)73例孕妇左侧卧位15°时下腔静脉内径[1.71(1.59,1.85)cm]大于平卧位时[1.37(1.22,1.52)cm],血流最高流速[23.73(20.22,28.59)cm/s]高于平卧位时[21.80(19.95,26.62)cm/s],差异均有统计学意义(n Z=7.274、2.108,n P值均0.05)。(2)73例孕妇中,行超声检查时出现SHS24例(32.87%)。有症状组和无症状组孕妇平卧位和左侧卧位15°时下腔静脉内径和血流最高流速以及子宫动脉脐动脉血流动力学参数比较,差异均无统计学意义(n P值均>0.05);两组孕妇年龄、孕次及产次差异均无统计学意义(n P值均>0.05),而有症状组孕妇的孕周、BMI及新生儿体质量均高于无症状组,差异均有统计学意义(n P值均0.05). Moreover, no significant differences in age, the number of pregnancies and the number of births were observed between the two groups (alln P values>0.05), and pregnant women with SHS had higher gestational weeks, BMIs and foetal weights (alln P values<0.05). (3) In the 24 pregnant women with SHS, the inner diameter and maximum blood flow velocity of the inferior vena cava on the 15° left lateral position were higher than those on the supine position (alln P values<0.05).n Conclusions:SHS may occur during the ultrasound examination of full-term pregnant women, the degree of compression of the inferior vena cava can be reduced, and the symptoms disappear when pregnant women immediately change to the left lateral position. The haemodynamics of the uterine and foetal umbilical arteries did not change, that is, the hypotension of pregnant women did not affect uterine placenta blood perfusion. Moreover, pregnant weeks, BMI of the pregnant woman and foetal weight may be influential factors for SHS.