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目的:探讨二甲双胍对食用高血糖生成指数食物的2型糖尿病患者糖代谢的影响。方法:对67例食用高生糖生成指数食物的2型糖尿病患者,使用二甲双胍加速糖代谢,观察治疗前及30、60、90 d患者空腹、餐后1 h、2 h、3 h血糖及糖化血红蛋白。结果:与治疗前比较,治疗第30,60,90天后患者空腹餐后1 h、2 h、3 h血糖峰值高度降低峰值时间推迟(P<0.05);糖化血红蛋白降低(P<0.001)。结论:二甲双胍能降低高血糖生成指数食物对糖尿病患者空腹血糖、餐后血糖和糖化血红蛋白。
AIM: To investigate the effect of metformin on glycometabolism in type 2 diabetic patients with hyperglycemic index food. Methods: Metformin was used to accelerate glucose metabolism in type 2 diabetic patients with food index of high glycemic index. The fasting, postprandial blood glucose at 1, 2, 3 h and glycosylated hemoglobin . Results: Compared with those before treatment, the peak time of peak height of blood glucose postprandial 1h, 2h, 3h postprandial postprandial postponed (P <0.05) and HbA1c decreased (P <0.001). Conclusion: Metformin can reduce fasting blood glucose, postprandial blood glucose and glycosylated hemoglobin in patients with diabetes mellitus with hyperglycemia index.