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Our report describes a previously healthy 10- year-old female whow as seen for urticarial plaques andmild loss of appetite. An initial laboratory workup re vealed an elevated leukocyte count of 30,000/μ L and a peripheral eosinophil co unt of 22,500/μ L.A skin biopsy showed a marked hypersensitivity tissue respons e with abundant eosinophils. Further investigation of her peripheral eosinophili a uncovered Giardia lamblia in a stool sample. Despite treatment with the anti- parasitic agent furazolidone, the patient’s urticarial plaques, leukocyte cou nt, and peripheral eosinophil count remained unchanged. A bone marrow biopsy con firmed a diagnosis of acute lymphoblastic leukemia (ALL). ALL with hypereosinoph ilia (ALL/Eo) represents a rare and distinct subset of ALL, with more than 30 ca ses documented in the literature. Our discussion summarizes the clinical aspects of this disease and reviews the reported dermatological manifestations of ALL/E o.
An initial laboratory workup re vealed an elevated leukocyte count of 30,000 / μL and a peripheral eosinophil co unt of 22,500 / μ LA skin Further investigations of her peripheral eosinophili a uncovered Giardia lamblia in a stool sample. Despite treatment with the anti- parasitic agent furazolidone, the patient’s urticarial plaques, leukocyte cou nt, and peripheral eosinophil count A remain unchanged unchanged. A bone marrow biopsy con firmed a diagnosis of acute lymphoblastic leukemia (ALL). ALL with hypereosinophilia (ALL / Eo) represents a rare and distinct subset of ALL, with more than 30 ca ses documented in the literature. summarizes the clinical aspects of this disease and reviews the reported dermatological manifestations of ALL / E o.