我国发生肝功能衰竭的主要原因是由肝炎病毒引起,而慢性重型乙型肝炎是其最常见的类型,占肝功能衰竭的90%以上[1],内科综合治疗病死率高达80%[2]。人工肝支持系统(ALSS)的应用为各类肝功能衰竭患者带来了生机[3]。我院采用ALSS(血浆置换)治疗慢性重型乙型肝炎48例患者,取得较满 The main cause of liver failure in our country is caused by hepatitis virus, while chronic severe hepatitis B is the most common type, accounting for more than 90% of liver failure [1], medical comprehensive cure mortality rate as high as 80% [2] . The use of artificial liver support system (ALSS) has brought vitality to patients with various types of liver failure [3]. In our hospital, 48 patients with chronic severe hepatitis B were treated with ALSS (plasma exchange)