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目的:探讨DN患者诊断中尿微量白蛋白、β2-微球蛋白检测的临床价值。方法:选取我院2013年1月-2013年6月收治的31例DN患儿,并选取到我院进行体检的健康儿童30例;两组人群分别为实验组和参考组,观察两组组患者的尿微量白蛋白和β2-微球蛋白水平。结果:实验组患儿的尿微量白蛋白和和β2-微球蛋白水平明显高于参考组,差异存在统计学意义(P<0.05)。尿病肾病患儿的尿微量白蛋白与β2-微球蛋白呈正相关性(r=0.601,P<0.05)。结论:检测患者尿微量白蛋白、β2-微球蛋白水平可有效诊断早期糖尿病肾病患者,对诊断患者病情有着较高的临床价值。
Objective: To investigate the clinical value of urine microalbumin and β2-microglobulin in diagnosis of DN patients. Methods: Totally 31 children with DN admitted to our hospital from January 2013 to June 2013 were selected and 30 healthy children were selected for physical examination in our hospital. The two groups were the experimental group and the reference group, and the two groups were observed Patients’ urine microalbumin and β2-microglobulin levels. Results: Urine microalbumin and β2-microglobulin levels in the experimental group were significantly higher than those in the reference group, with statistical significance (P <0.05). Urine microalbuminuria was positively correlated with β2-microglobulin in children with diabetic nephropathy (r = 0.601, P <0.05). Conclusion: The detection of urinary albumin and β2-microglobulin in patients with early diabetic nephropathy can diagnose early patients with diabetic nephropathy, which has a high clinical value for the diagnosis of patients.