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目的探讨成分输血在肝硬化食管胃底静脉曲张破裂出血中的应用。方法对125例肝硬化食管胃底静脉曲张破裂出血患者分为成分输血组、全血输血组,治疗前后进行血液学指标血红蛋白(HGB)、红细胞数(RBC)、红细胞比容(HCT)、血小板数(PLT)、凝血酶原时间(PT)、活化部分凝血活酶时间(APTT)以及纤维蛋白原(FGB)检测和即发不良反应及输血后并发症的比较。结果成分输血组患者治疗后血液学HGB、RBC、HCT、Plt、PT、APTT以及FGB七项指标与输血前比较明显好转(P均<0.01),成分输血组不良反应的发生率明显低于输全血组(P<0.05)。结论合理使用各种成分血液制品治疗肝硬化食管胃底静脉曲张破裂出血较输全血安全有效。
Objective To explore the application of component blood transfusion in the treatment of patients with esophageal and gastric variceal bleeding due to cirrhosis. Methods 125 patients with cirrhosis esophagogastric variceal bleeding were divided into transfusion group and whole blood transfusion group. Before and after treatment, hematological indexes such as hemoglobin (HGB), RBC, hematocrit (HCT), platelet PLT, PT, APTT and fibrinogen (FGB) were measured. The adverse reaction and the complication after transfusion were compared. Results The hematological parameters of hematology, such as HGB, RBC, HCT, Plt, PT, APTT and FGB in the constituent blood transfusion group were significantly improved after transfusion (all P <0.01), and the incidence of adverse reactions in the constituent blood transfusion group was significantly lower than that before transfusion Whole blood group (P <0.05). Conclusion The rational use of various components of blood products in the treatment of cirrhosis esophageal varices bleeding more safe and effective than the whole blood transfusion.