论文部分内容阅读
高效价抗葡萄球菌免疫血浆(ACΠ)被广泛用来治疗化脓性外科感染。但是,人们在临床上对ACΠ总是与其他治疗方法相结合来使用的。因此,对ACΠ的作用,及其对中性粒细胞受体状态的影响,实际上还缺乏综合研究。作者使用了自己拟定的实验性葡萄球菌感染的模型,专门研究了ACΠ制剂对吞噬细胞(中性粒细胞)系统以及对T-和B-淋巴细胞及其亚群水平的各种作用。材料与方法:给体重为300-350克的豚鼠肌注10~(10)个金黄葡萄球菌细胞,引起非致命的全身感染,接着在接种后的第1、第3和第5天,向其中一半的豚
High-potency anti-staphylococcal immune plasma (ACΠ) is widely used to treat septic surgical infections. However, the clinical use of ACΠ is always combined with other therapies. Therefore, the role of ACΠ, and its impact on neutrophil receptor status, in fact, the lack of comprehensive study. The authors used their own model of experimental staph infection to specifically examine the various effects of ACΠ agents on phagocyte (neutrophil) systems and on the levels of T- and B-lymphocytes and their subsets. MATERIALS AND METHODS: Guinea pigs weighing 300-350 g were intramuscularly injected with 10 to 10 Staphylococcus aureus cells, causing a non-fatal systemic infection, followed by 1, 3 and 5 days after inoculation Half of the dolphin