用醋酸纤维薄膜电泳研究直肠乳头状腺癌及癌旁粘膜的乳酸脱氢酶(LDH)同工酶酶谱。癌的LDH-5分配百分比显著增高,癌周围粘膜的LDH-5逐渐降低。恶性病变中LDH-5的升高可以解释其以无氧酵解为主的代谢特征,有人认为酶谱改变先于病征性的形态学变化出现,故此可能有助于手术中决定的外观正常的肠段应切除的范围, Acetylcellulose membrane electrophoresis was used to investigate the lactate dehydrogenase (LDH) isozyme patterns of rectal papillary adenocarcinoma and paraneoplastic mucosa. The distribution percentage of LDH-5 in cancer was significantly increased, and LDH-5 in the surrounding mucosa of the cancer gradually decreased. The increase of LDH-5 in malignant lesions can explain its metabolic characteristics mainly in anaerobic glycolysis. Some people think that the zymogram change precedes the morphological changes of the symptoms. Therefore, it may help to determine the normal appearance of the surgery. The extent to which the bowel should be removed,