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近年来我们应用CCI。建立肝纤维化大鼠模型,同时投予木同剂量抗氧化剂VitE,观察其对胶原合成的影响,以及肝内的病理变化,以探讨VitE预防肝纤维化的可能机制。材料和方法动物和试剂:SD雄性大鼠6O只,平均体重200士529。40%CCI。石腊油溶液自制,VitE注射液(上海第九制药
In recent years we use CCI. To establish a rat model of hepatic fibrosis and administer the same dose of vitamin E as VitE to observe its effect on collagen synthesis and pathological changes in the liver to explore the possible mechanism of VitE in preventing liver fibrosis. Materials and Methods Animals and Reagents: Sixty SD male rats weighing 200 ± 529.40% CCI. Made of paraffin oil solution, VitE injection (Shanghai Ninth Pharmaceutical