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本文报道甲灭酸(Mefenamic acid)可引起白细胞减低。作者在6个月中遇见5例(78～89岁)与应用甲灭酸有关的白细胞减少。2例用了推荐的成人量—1.5/天,2例0.5、每晚一次,一例1.0/天。在治疗开始后6天～5周检测有白细胞数减少(<4000/mm~3)。
Mefenamic acid is reported to cause leukopenia. The authors met 5 patients (78-89 years) with leucovorin-related leukopenia in 6 months. The recommended adult dose was 1.5 / day in 2 cases, 0.5 in 2 cases, once per night, and 1.0 / day in one case. The number of white blood cells was reduced from 6 days to 5 weeks after the start of treatment (<4000 / mm ~ 3).