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我院于1987～1994年间用普鲁卡因静滴治疗咯血,并与同期内其他常用止血剂(止血芳酸、止血敏、安络血)治疗作对比,疗效观察如下:一般资料:各种原因引起咯血的住院病人随机分二组:普鲁卡因静滴治疗组(简称治疗组)138例,其中男84例,女54例,年龄17～76岁,平均49岁.原发病为肺结核69例,支气管扩张症27例,慢性支气管炎24例,肺脓肿9例,肺炎6例,原因不明者3例.其中大量咯血39例(大于500ml/d),中量咯血75例(200～500ml/d),小量咯血24例(小于200ml/d).常规止血剂治疗组(简称对照组),72例,性别、年龄、原发病、咯血量均与治疗组相类似.方法:用药前做普鲁卡因皮试,阴性者予0.5%盐酸普鲁卡因针100ml,共0.5克,加入生理盐水500ml中,以每分钟16滴速度静滴,每日二次,待奏效后改为每日一次,再用三天.连用一周,未见效者停用.
In our hospital from 1987 to 1994 with intravenous procaine intravenous hemoptysis, and with other commonly used in the same period hemostatic agent (antithrombotic acid, Zhiganmiao, anorexia blood) for treatment compared to the following observations: The general information: a variety of Cause of hemoptysis hospitalized patients were randomly divided into two groups: intravenous procaine treatment group (referred to as the treatment group) 138 cases, 84 males and 54 females, aged 17 to 76 years, mean 49. The primary disease was 69 cases of pulmonary tuberculosis, bronchiectasis in 27 cases, chronic bronchitis in 24 cases, pulmonary abscess in 9 cases, pneumonia in 6 cases, 3 cases of unknown cause, including a large number of hemoptysis in 39 cases (greater than 500ml / d) ~ 500ml / d), and a small amount of hemoptysis in 24 cases (less than 200ml / d) .Conventional hemostat treatment group (control group), 72 cases, gender, age, primary disease, hemoptysis volume were similar to the treatment group. : Before the drug to do procaine skin test, negative to 0.5% procaine hydrochloride needle 100ml, a total of 0.5 grams, added 500ml of normal saline intravenously at a rate of 16 drops per minute, twice daily, to be effective After the change to once a day, and then three days for one week, no effect disabled.