目的:探讨生活干预对单纯性肥胖者非酒精性脂肪肝的逆转作用。方法:对60例以B超诊断为脂肪肝的单纯性肥胖者给予为期6个月的严格饮食控制及规律体育锻炼,评价治疗后体重下降对脂肪肝转归的影响。结果:随着患者体重指数的下降,腰围减小、胰岛素敏感性指数升高,脂肪肝严重程度得到改善。结论:脂肪肝是肥胖者常见的并发症,生活方式干预是治疗单纯性肥胖者非酒精性脂肪肝的有效方法。 Objective: To investigate the reversal effect of life intervention on non-alcoholic fatty liver in simple obesity. Methods Sixty months of strict diet control and regular physical exercise were given to 60 simple obesity patients diagnosed as B-type fatty liver by B-ultrasound. The effect of weight loss on the outcome of fatty liver after treatment was evaluated. Results: With the decline of body mass index, waist circumference and insulin sensitivity index increased, the severity of fatty liver was improved. Conclusion: Fatty liver is a common complication of obesity, lifestyle intervention is an effective method for the treatment of non-alcoholic fatty liver of simple obesity.