饲喂家兔胆固醇造成实验性动脉粥样硬化,模型组每只动物均以主动脉病变严重,肺动脉AS斑块主要由泡沫细胞组成。病变严重时,中膜浅层平滑肌细胞可于原处转变为泡沫细胞。心冠动脉各级分枝受累程度与服用胆固醇时间长短密切相关,服用时间越长,受累程度越严重,以<0.1mm之分枝最明显。 Cholesterol was fed to rabbits to cause experimental atherosclerosis. The aortic lesions were severe in each animal in the model group, and the AS plaques in the pulmonary arteries were mainly composed of foam cells. When the lesions are severe, the smooth muscle cells in the superficial layer of the media can be transformed into foam cells in situ. The degree of coronary arterial involvement at each level of the coronary arteries is closely related to the length of time taken for cholesterol. The longer the time of administration, the more severe the degree of involvement, with the most obvious branching of <0.1 mm.