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目的 探讨茵栀黄汤联合双歧杆菌三联活菌治疗新生儿黄疸的疗效.方法 收集本院2015年6月到2017年6月收治的106例新生儿黄疸病例,以数字法随机分成观察组(53例)和对照组(53例).对照组给予常规治疗,观察组在对照组的基础上施以茵栀黄汤联合双歧杆菌三联活菌辅助治疗,对比观察两组患者的临床疗效,血清胆红素,血清转铁蛋白及酶指标,T淋巴细胞CD3+与CD4+及CD8+指标.结果 观察组患儿的痊愈率为50.94%(27/53),总有效率为94.34%(50/53),均显著高于对照组的22.64%(12/53)、79.25%(42/53),差异均有统计学意义(P0.05).治疗后,两组患儿TBA、TBIL、DBIL以及CK、CK-MB、AST、LDH和CD8+均较治疗前明显下降,且观察组患儿下降幅度均优于对照组,差异均有统计学意义(P<0.05);而TRF、CD3+、CD4+及CD4+/CD8+较治疗前明显升高,且观察组患儿升高幅度优于对照组,差异均有统计学意义(P<0.05).两组治疗后均未出现明显的不良反应.结论 茵栀黄汤联合双歧杆菌三联活菌对新生儿黄疸的疗效显著,对患儿的血清学指标及免疫功能均有较好的改善作用,值得临床借鉴.“,”Objective To study of Yinzhihuang decoction combined with Bifidobacterium triple viable in treatment of neonatal jaundice. Methods From June 2015 to June 2017,a total of 106 cases of neonatal jaundice in our hospital were randomly divided into observation group(53 cases)and control group(53 cases). The control group was given routine the treatment;for the observation group,on top of the routine treatment as the control group,the patients were treated with Yinzhihuang decoction combined with Bifidobacterium triple viable adjuvant therapy. Serum bilirubin ,serum transferrin and enzyme index,CD3+and CD4+T lymphocytes and CD8+index of patients were measured. Results The cure rate in the observation group was 50.94%(27/53)and the total effective rate was 94.34%(50/53),which were significantly higher than those in the control group[(22.64%(12/53),79.25%(42/53)](P0.05). After treatment,TBA,TBIL,DBIL,CK,CK-MB,AST,LDH and CD8+ in both groups were significantly lower than those before treatment,and the decrease in the observation group was better than that in the control group(P<0.05). However,the levels of TRF,CD3+,CD4+and CD4+/CD8+in the observation group were significantly higher than those in the control group (P<0.05). The was no obvious adverse reaction after treatment in both groups. Conclusion Yinzhihuang decoction combined with Bifidobacterium triple viable could effectively treat neonatal jaundice in children,and could improve the serum index and immune function of the children;it is worthy as clinical reference.