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结缔组织生长因子(connective tissue growth factor,CT-GF)是近年来新发现的一种间质细胞的生长因子,具有明显的丝裂原性和趋化性,可以启动一系列介导组织创伤修复和再生的生物学过程。作为转化生长因子(transforming growthfactorβ1,TGF-β1)的下游反应元件,CTGF介导TGF-β1
Connective tissue growth factor (CT-GF) is a newly discovered stromal cell growth factor in recent years. It has obvious mitogenicity and chemotaxis and can initiate a series of mediators that mediate tissue injury And regeneration of biological processes. As a downstream response element of transforming growth factor β1 (TGF-β1), CTGF mediates TGF-β1