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目的 研究血浆粘度对胃粘膜血流的影响。方法 选择无心血管、肝、肾及内分泌系统疾病的慢性胃炎患者 80例 ,用激光多普勒血流仪测定病人胃粘膜血流 (GMBF) ,同时检测病人血流变学各指标。结果 老年人GMBF明显低于年轻人 (P<0 .0 1) ,老年人血浆粘度 (BV)比年轻人高 (P<0 .0 5 ) ,且与胃粘膜血流呈负相关。结论 血浆粘度直接影响胃微循环灌注 ,且随年龄增加而升高 ,这可间接影响胃粘膜的修复和愈合 ,在胃肠疾病的治疗中 ,血浆粘度不容忽视 ,它是引起老年人胃粘膜血流下降的原因之一。
Objective To study the effect of plasma viscosity on gastric mucosal blood flow. Methods Eighty patients with chronic gastritis without cardiovascular, hepatic, renal and endocrine diseases were selected. The gastric mucosal blood flow (GMBF) was measured by laser Doppler flowmetry and the hemorrheological parameters were measured. Results The GMBF of the elderly was significantly lower than that of the young (P0.01). The plasma viscosity (BV) of the elderly was higher than that of the young (P0.05), and negatively correlated with the gastric mucosal blood flow. Conclusion The plasma viscosity directly affects gastric microcirculation perfusion, and increases with age, which may indirectly affect the repair and healing of gastric mucosa. In the treatment of gastrointestinal diseases, the plasma viscosity can not be ignored, it is caused by gastric mucosal blood in the elderly One of the reasons for the declining stream.