作者在长期对穿凿性毛囊炎病例的研究中遇到一女孩有毛发角化病。数周以后发展为淋巴网状细胞肉瘤(何杰金氏病)。患者为14岁白种女孩,1971年6月来诊。主诉为最近6个月在臂、大腿和臀部痒感增加,发生硬的红色丘疹,而过去从未有过任何皮肤病症。皮肤科的检查发现在臂、大腿的伸面和臀部有播散的1～3毫米大小的红色锥形毛囊性丘疹伴有 The author encountered a girl with chronic keratoderma in a long-term study of chisel-folliculitis cases. A few weeks later it developed lymphoblastoid sarcoma (Hodgkin’s disease). The patient was a 14-year-old Caucasian girl who came to the clinic in June 1971. The chief complaint was an increase in itching in the arms, thighs, and buttocks in the last 6 months, with hard red pimples and no past skin conditions. Examination of the dermatologist revealed disseminated red cone-shaped follicular papules accompanied by disseminated 1-3 mm in the extension surfaces and buttocks of the arms and thighs.