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目的:通过分析中心性浆液性脉络膜视网膜病变(Central Serous Chorioretinopathy,CSCR)的吲哚青绿血管造影(Indocyanine Green Angiography,ICGA)特征,探讨该病的病理特点及治疗机理。方法:使用海德堡血管造影仪对35例临床诊断为CSCR患者进行ICGA及眼底荧光血管造影(FFA)同步分析,解释和讨论造影结果。结果:35例病例中,有29例(83％)在ICEA中发现的病灶超过FFA所见病灶数,25例(71.4％)为双眼,所有FFA的病灶处均有ICGA改变,且ICGA所见病灶范围大于FFA病变。结论:脉络膜通透性改变是中浆的早期改变,由此引起其上方视网膜色素上皮(RPE)功能失代偿和缺损可能是中浆的主要发病机制。中浆的激光和药物治疗效果和原理需要进一步探讨。眼科学报1999;15:81—84。
OBJECTIVE: To investigate the pathological features and mechanism of the disease by analyzing the characteristics of Indocyanine Green Angiography (ICGA) in central serous chorioretinopathy (CSCR). Methods: 35 patients with clinically diagnosed CSCR were analyzed by ICGA and fundus fluorescein angiography (FFA) simultaneously using Heidelberg angiography, and the results of angiography were explained and discussed. RESULTS: Of the 35 cases, 29 (83%) had lesions found in ICEA exceeding the number found in FFA, 25 (71.4%) were eyes, all had ICGA changes at the lesion site, and ICGA findings Focal lesions larger than FFA lesions. CONCLUSIONS: Changes in choroidal permeability are early changes in the mid-pulp, which leads to functional decompensation and defect of the RPE above it, which may be the main pathogenesis of the pulp. Pulp laser and drug treatment efficacy and principles need further study. Journal of Ophthalmology 1999; 15: 81-84.