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作者研究抗淋巴细胞免疫球蛋白(АЛГ)治疗过程中的16例再生障碍性贫血患者(再障)的止血系统。АЛГ加入0.85%氯化钠250ml中静脉滴注,1—3mg/kg/日,一疗程7—9次。再障病人滴注АЛГ前血小板显著减少,血浆复钙时间、血浆肝素耐量,凝血酶原复合物活性,血浆纤维蛋白原浓度等11项指标表明患者处于低凝状态,有隐袭的弥漫性血管内凝血(DIC),接受АЛГ治疗后,全血纤溶活性降低,
The authors studied the hemostatic system in 16 patients with aplastic anemia (AA) during anti-lymphocyte immunoglobulin (АЛГ) treatment. АЛГ added 0.85% sodium chloride 250ml intravenous infusion, 1-3mg / kg / day, a course of 7-9 times. Aplastic anemia patients before АЛГ significantly reduced platelet count, plasma calcium reperfusion time, plasma heparin, prothrombin complex activity, plasma fibrinogen concentration and other 11 indicators show that patients in the low coagulation state, with insidious diffuse blood vessels Internal coagulation (DIC), after receiving АЛГ treatment, decreased whole blood fibrinolytic activity,