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目的探讨抗菌药物围术期应用联合术中聚维酮碘宫腔擦洗在预防剖宫产术后感染方面的临床价值。方法 160例行剖宫产术分娩的产妇,按入院时间随机分为观察组和对照组,各80例。对照组单纯预防性应用抗生素,观察组在对照组基础上在术中进行聚维酮碘宫腔擦洗。观察比较两组患者的术后发热、切口感染及白细胞计数情况。结果观察组患者术后发热11例,发热率为13.75%;对照组患者术后发热24例,发热率为30.00%,两组比较差异具有统计学意义(P<0.05)。术后48 h进行血常规分析,观察组患者的白细胞计数明显低于对照组,差异具有统计学意义(P<0.05);同时观察两组患者术后3 d切口感染情况,对照组患者感染率为11.25%,观察组患者感染率为2.50%,两组比较差异具有统计学意义(P<0.05)。结论围手术期应用抗生素联合术中聚维酮碘擦洗宫腔对预防产妇剖宫产术后感染有一定的临床意义,应当临床推广并继续深入研究。
Objective To investigate the clinical value of perioperative antibacterials combined with intraoperative povidone-iodine intrauterine scrub in the prevention of infection after cesarean section. Methods A total of 160 maternal women delivered by cesarean section were randomly divided into observation group and control group according to the time of admission. The control group was treated with prophylactic antibiotics only. The observation group was scrubbed with Povidone Iodine intraoperatively on the basis of the control group. Postoperative fever, incision infection and white blood cell count were observed and compared between the two groups. Results In the observation group, 11 cases had fever after operation, the rate of fever was 13.75%. In the control group, 24 cases were fever after operation and the rate of fever was 30.00%. There was significant difference between the two groups (P <0.05). The blood routine analysis was performed at 48 hours after operation. The white blood cell count in the observation group was significantly lower than that in the control group (P <0.05). At the same time, the incision infection at 3 days and the infection rate in the control group Was 11.25%. The infection rate in the observation group was 2.50%. The difference between the two groups was statistically significant (P <0.05). Conclusion Perioperative antibiotics combined intraoperative polyvidone iodine scrubbing the uterine cavity for the prevention of postpartum infection of cesarean section has some clinical significance, it should be clinical and further study.