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已知麦角衍生物治疗后会发生腹膜后纤维变性副作用。溴隐亭导致纤维变性则罕有报道。根据文献报道和个人联系,在数万例溴隐亭治疗病例中,继发腹膜后纤维变性者仅7例,胸膜—肺纤维变性稍多些,约90例。而发生纤维变性的机制尚不明了。纤维变性每易发生于溴隐亭大剂量(140mg/天)或长期(10年)应用之后。本文报道1例如下:男,67岁,1984年因帕金森病应用左旋多巴等6年效果欠佳加用溴隐亭30mg/天,1986年底又加用丙炔苯丙胺。其时出现不明原因的炎症综合征(血沉加速71/
Known ergot derivatives treatment of retroperitoneal fibrosis will occur side effects. Bromocriptine causes fibrosis is rarely reported. According to the literature and personal contact, in the tens of thousands of cases of bromocriptine treatment, only 7 cases of retroperitoneal fibrosis, pleural - pulmonary fibrosis slightly more, about 90 cases. The mechanism of fibrosis is unclear. Fibrosis often occurs after high doses of bromocriptine (140 mg / day) or long-term (10 years) application. This article reports a case as follows: male, 67 years old, 1984, due to Parkinson’s disease, levodopa and other 6-year effect is not good plus bromocriptine 30mg / day, by the end of 1986 plus propyne amphetamine. There was an unexplained inflammatory syndrome (ESR 71 /