论文部分内容阅读
目的探讨弥可保（甲基维生素Ｂ１２）对损伤神经的促神经再生作用并与维生素Ｂ１２的疗效相比较。方法对急诊前臂神经切割伤２３例３５根神经（正中神经１７根，尺神经１８根），根据入院时间随机分成２组：（Ａ）维生素Ｂ组：神经缝合术后肌肉注射维生素Ｂ１２５００μｇ／次，隔日１次；２个月后改长期口服维生素Ｂ１，Ｂ６各１０ｍｇ／次，每日１次。（Ｂ）弥可保组：神经缝合术后肌肉注射弥可保５００μｇ／次，隔日１次；２个月后改长期口服弥可保５００μｇ／次，每日３次。术后平均随访７个月进行肌电图检测，测定神经运动电位、感觉电位的潜伏期和波幅。结果两组相比，除正中神经运动电位潜伏期和尺神经感觉电位波幅无明显差别外，其余各指标，弥可保组均优于维生素Ｂ组。结论弥可保对周围神经损伤后有促进其恢复的作用。
Objective To investigate the neurotrophic effects of methystosin (B12) on injured nerves and to compare with the curative effect of vitamin B12. Methods Twenty-three patients (23 nerves, 17 nerves and 18 ulnar nerves) of emergency forearm nerve incision were randomly divided into 2 groups according to the time of admission: (A) Vitamin B group: intramuscular injection of vitamin B12500 μg / Once every other day; 2 months after the change of oral vitamin B1, B6 each 10mg / time, 1 day. (B) Mi Kebao group: after intramuscular nerve suture intramuscular injection of 500μg / sec, once every other day; 2 months after the change of long-term oral methycobal 500μg / times, 3 times a day. After a mean follow-up of 7 months, EMG test was performed to measure the latency and amplitude of nerve motor potentials and sensory potentials. Results There was no significant difference between the two groups except for the latency of median motor neuron potential and the amplitude of ulnar nerve sensory potential, and the other indexes were better than that of vitamin B group. Conclusion Miocao can promote the recovery of peripheral nerve after injury.