利培酮属于抗精神失常类药物,为苯并异恶唑衍生物,具有独特性质的选择性单胺能拮抗剂[1],临床上用于治疗急性和慢性精神分裂症以及其他各种精神病症状的阳性症状。目前利培酮片含量采用高效液相色谱法(HPLC)测定[2],但方法较为复杂。我们参照文献[3,4]采用高效毛细管区带电泳方 Risperidone belongs to the class of antipsychotics, which is a benzisoxazole derivative, a selective monoaminergic antagonist with unique properties [1], which is clinically used in the treatment of acute and chronic schizophrenia and other various psychiatric disorders Symptoms of positive symptoms. At present, the content of risperidone tablets by high performance liquid chromatography (HPLC) [2], but the method is more complicated. We refer to the literature [3,4] using high-performance capillary zone electrophoresis