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[目的]分析启东市2001~2007年全人群食管癌登记病例生存率,为预后评价及防治提供依据。[方法]929例食管癌登记病例的生存(死亡)情况随访截止于2009年12月31日;剔除只有死亡医学证明(DCO)病例,实际纳入分析916例。用SURV3.01软件计算5年观察生存率(OS)及5年相对生存率(RS)。[结果]食管癌1、3、5年OS分别为26.20%、12.79%、10.66%,1、3、5年RS分别为27.85%、15.33%和14.45%。其中男性1、3、5年RS分别为28.56%、15.65%、14.70%,女性1、3、5年RS分别为26.30%、14.63%、13.87%,男女性生存率差别无显著意义(P>0.05)。15~34岁、35~44岁、45~54岁、55~64岁、65~74岁及75岁以上各年龄组的5年RS分别为33.44%、14.59%、19.07%、19.43%、11.11%及12.00%。男、女性食管癌5年RS(14.70%与13.87%)显著高于启东1972~2000年的4.38%与5.57%。[结论]过去几十年中启东市全人群食管癌登记病例总体生存率有较大的提高,相当于国内城市地区90年代的水平,与国外发达国家的差距也在缩小。
[Objective] To analyze the survival rate of registered esophageal cancer patients from 2001 to 2007 in Qidong and to provide evidences for the prognosis evaluation and prevention. [Methods] The survival (death) of 929 cases of esophageal cancer was followed up on December 31, 2009. Only cases of death medical certificate (DCO) were excluded, and 916 cases were actually included in the analysis. SURV3.01 software was used to calculate 5-year OS and 5-year relative survival (RS). [Results] The 1, 3, 5-year OS of esophageal cancer was 26.20%, 12.79% and 10.66%, respectively, and the RSs were 27.85%, 15.33% and 14.45% respectively in 1,3 and 5 years. The 1, 3, 5-year men’s RS were 28.56%, 15.65% and 14.70%, respectively. The 1, 3 and 5-year women’s RS were 26.30%, 14.63% and 13.87% respectively. There was no significant difference between male and female survival rates (P> 0.05). The 5-year RS of 15 to 34 years old, 35 to 44 years old, 45 to 54 years old, 55 to 64 years old, 65 to 74 years old and 75 years old and above are respectively 33.44%, 14.59%, 19.07%, 19.43% and 11.11 % And 12.00% respectively. The 5-year RS (14.70% vs 13.87%) of esophageal cancer in men and women was significantly higher than 4.38% and 5.57% in Qidong from 1972 to 2000. [Conclusion] The overall survival rate of esophageal cancer registration among the whole population in Qidong has been greatly increased over the past few decades, which is equivalent to the level of 90 years in urban areas of China and the gap with developed countries in the world is narrowing.