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1973年3月以来,我们采用2.5%穿心莲内酯注射液与异菸肼治疗结核性脑膜炎70例,比过去用链霉素、异菸肼和PAS的疗效较好,病死率显著下降。现介绍如下: 临床资料1973年3月～1975年5月,经临床和化验确诊为结核性脑膜炎的住院患者70例。其中男43例,女27例。年龄最小4个月,最大62岁。1～14岁40例,占57.14%。初发59例,复发11例。入院病情:轻型8例,中型16例,重型46例。并发症:颅内压增高21例,肺结核12例,肺部感染7例,消化道出血6例,肠道感染4例,尿路感染4例,中毒性肝炎4例,营养不良16例,视神经萎缩12例,肢体瘫痪17例,低血钾12例,心肌炎2例,精神症状3例,尿崩症1例。治疗结果:临床治愈30例,有效34例,死亡6例。
Since March 1973, we treated 2.5% andrographolide injection with isoniazid in 70 patients with tuberculous meningitis, which was more effective than the past with streptomycin, isoniazid and PAS, and the mortality rate dropped significantly. Are introduced as follows: Clinical data March 1973 ~ May 1975, clinically and laboratory confirmed tuberculosis meningitis inpatients 70 cases. There were 43 males and 27 females. The youngest 4 months, maximum 62 years old. 1 to 14 years old in 40 cases, accounting for 57.14%. The first episode of 59 cases, 11 cases of recurrence. Admission conditions: 8 cases of light, 16 cases of medium-sized, 46 cases of heavy. Complications: Elevated intracranial pressure in 21 cases, tuberculosis in 12 cases, pulmonary infection in 7 cases, gastrointestinal bleeding in 6 cases, intestinal infection in 4 cases, urinary tract infection in 4 cases, toxic hepatitis in 4 cases, malnutrition in 16 cases, optic nerve 12 cases of atrophy, limb paralysis in 17 cases, hypokalemia in 12 cases, myocarditis in 2 cases, psychiatric symptoms in 3 cases, diabetes insipidus in 1 case. Treatment outcome: clinical cure in 30 cases, effective in 34 cases, 6 cases of death.