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FDA报告抗精神病药物齐拉西酮与罕见但可能致命的皮肤反应相关齐拉西酮是一种用于治疗严重精神疾病、精神分裂症和Ⅰ型双相情感障碍的抗精神病药物。FDA警示齐拉西酮(商品名Geodon)及其仿制药与一种罕见但严重的皮肤反应相关。FDA在Geodon药品说明书的“警告与注意事项”中已增加一条新的警示,描述了这种称为伴嗜酸粒细胞增多和系统症状的药物反应(DRESS)的严重疾病。出现发热伴随皮疹或淋巴结肿大的患者应立即就医。如怀疑DRESS,应立即停止齐拉西酮治疗(2014-12-11,http://www.fda.gov/Drugs/DrugSafety/ucm426391.htm)。
FDA reports ziprasidone, an antipsychotic drug, is associated with a rare but potentially deadly skin reaction Ziprasidone is an antipsychotic medication used to treat severe mental illness, schizophrenia and type I bipolar disorder. The FDA warned that ziprasidone (Geodon) and its generic drugs are associated with a rare but severe skin reaction. The FDA has added a new warning to Geodon’s drug warranties, “Warnings and Precautions,” describing a serious condition called DRESS with eosinophilia and systemic symptoms. Patients who develop fever with rash or swollen lymph nodes should seek medical attention immediately. If you suspect DRESS, ziprasidone therapy should be stopped immediately (2014-12-11, http://www.fda.gov/Drugs/DrugSafety/ucm426391.htm).