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目的:探究硫普罗宁治疗非酒精性脂肪肝的临床疗效。方法:选取本院2012年1月-2013年12月收治的200例非酒精性脂肪肝患者.将患者完全随机均分为实验组和对照组两组,对实验组患者采取硫普罗宁治疗,对对照组患者采取常规井底丹参、静推维生素C进行治疗,治疗时间为3个月。对两组患者治疗前后的影像学检查结果、血清转氨酶水平及血脂等水平进行对比分析。结果:实验组患者治疗后的血清转氨酶水平、总胆固醇含量及三酰甘油水平相比于对照组更接近正常水平,两组差异比较差异有统计学意义(P<0.05)。结论:硫普罗宁治疗非酒精性脂肪肝治疗效果显著,安全性高,值得在临床范围内大力推广。
Objective: To investigate the clinical efficacy of tiopronin in the treatment of non-alcoholic fatty liver disease. Methods: A total of 200 non-alcoholic fatty liver patients who were admitted to our hospital from January 2012 to December 2013 were randomly divided into two groups: experimental group and control group. The patients in experimental group were treated with tiopronin, The control group of patients take conventional well Salvia, push the vitamin C for treatment, the treatment time was 3 months. Before and after treatment of the two groups of patients with imaging findings, serum aminotransferase levels and lipid levels were compared. Results: The levels of serum aminotransferase, total cholesterol and triglyceride in experimental group were closer to normal than those in control group. There was significant difference between the two groups (P <0.05). Conclusion: The treatment of non-alcoholic fatty liver with tiopronin is effective, safe and worthy of promotion in the clinical scope.