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超分割放射治疗食管癌的前瞻性临床研究山西省肿瘤医院（０３００１３）张佩怀，王瑛，王鹤皋，赵瑞芬，陈绍兰，郝颖坤，王玉，王中敏，王保平，程秉兰分割照射食管癌的临床效果如何，我们与常规照射进行了比较。现将其近斯疗效报道如下：材料和方法１９８６年１月至１９８６年１２月将放射治疗４２例食管癌患者分为超分割照射和常规照射的对照性研究。病例就食管癌临床分期和病理类型按配对设计原则，随机分成两组，各２１例（见表１）。随访时间在三年以上，失访自随访日期起作死亡统计。４２例患者中，男３０例，女１２例，男女之比２．５：１，两组年龄３０～７０岁，４０～６０岁占８０．９％。１．照射方法：采用６０Ｃｏ及１０ＭＶ—ｘ线体外照时，全部均采用三野同中心照射。经模拟机定位，设前野垂直，野宽为６厘米。背部两个斜野，野宽５厘米。长度按病变两端各延长３～４厘米。２．照射剂量：①超分割组：每次１１５ＣＧＹ，每日二次，两次之间隔６～８小时，每周照射五天，肿瘤量ＤＴ８０ＧＹ。②常规照射组：每次１９０～２００ＣＧＹ，每天一次，每周五次，肿瘤量ＤＴ７０ＧＹ。结果１．治疗结束采用食管摄片进行疗效评定，按照Ｎ８１年郑州会议讨论的四级分类标准两组分析比较，满意加
Prospective clinical study of hyperfractionated radiation therapy for esophageal cancer Shanxi Provincial Tumor Hospital (030013) Zhang Peihuai, Wang Hao, Wang Hexi, Zhao Ruifen, Chen Shaolan, Hao Yingkun, Wang Yu, Wang Zhongmin, Wang Baoping, Cheng Binglan Clinical efficacy of segmented irradiation of esophageal cancer, we Compared with conventional irradiation. The current curative effects of recent illnesses are reported as follows: Materials and Methods Forty-two patients with esophageal cancer treated with radiotherapy were divided into control and contrast studies from January 1986 to December 1986. Cases were randomly divided into two groups, 21 cases (Table 1), according to the principle of paired design for clinical stage and pathological type of esophageal cancer. The follow-up time was more than three years, and the death statistics were recorded since the follow-up date. Of the 42 patients, 30 were males and 12 were females. The ratio between males and females was 2.5:1. The two groups were aged 30 to 70 years and 40 to 60 years old accounted for 80.9%. 1. Irradiation method: When using the 60Co and 10MV-x rays in vitro, all were irradiated with three fields. After the simulation machine positioning, set the vertical field, the width is 6 cm. Two slanting backs, 5 cm wide. The length of the lesion is extended by 3 to 4 cm at each end of the lesion. 2. Irradiation dose: 1 hyperfractionated group: 115 CGY each time, twice daily, twice at intervals of 6 to 8 hours, and irradiated for five days per week, and the tumor volume was DT80GY. 2 conventional irradiation group: Each time 190 ~ 200CGY, once a day, five times a week, tumor volume DT70GY. Results 1. At the end of the treatment, esophageal radiography was used to evaluate the efficacy, and according to the four-level classification criteria discussed at the N81 Zhengzhou meeting, the two groups were compared and satisfied.