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采用在活体内微透析技术，观察大鼠在不同强度运动时及运动后尾核细胞外液中多巴胺（ＤＡ）及其代谢产物３．４一二羟笨乙酸（ＤＯＰＡＣ）和高香草酸（ＨＶＡ）含量的变化。结果表明，运动时尾核细胞外液中以ＤＯＰＡＣ含量增高；运动后细胞外液中ＤＡ、ＤＯＰＡＣ和ＨＶＡ含量均增高，其中ＤＯＰＡＣ和ＮＶＡ的增高程度取决于运动速度。提示尾核多巴胺代谢与运动强度有关。
In vivo microdialysis technique was used to observe the effects of dopamine (DA) and its metabolites 3.4-dihydroxyterephthalic acid (DOPAC) and homovanillic acid (HVA) ) Content changes. The results showed that the content of DOPAC increased in the extracellular fluid of caudate nucleus during exercise, and the contents of DA, DOPAC and HVA in the extracellular fluid increased after exercise. The increase of DOPAC and NVA was dependent on the velocity of exercise. Tip caudate nucleus dopamine metabolism and exercise intensity.