目的　探讨电化学治疗肝癌的疗效和副作用。方法　 2 6例肝癌患者接受B超引导下电化学治疗 ,观察治疗前后患者的临床表现、肿物大小、甲胎球蛋白 (AFP)水平、组织病理学、免疫指标以及肝肾功能和血常规的变化。结果　治疗后临床症状减轻 ,AFP水平下降 ,细胞免疫功能增强。组织学示治疗区肿瘤组织完全或部分坏死、纤维化。完全缓解 (CR) 2例 ,部分缓解 (PR) 13例 ,好转 (MR) 2例 ,稳定 (SD) 7例 ,进展 (PD) 2例 ,总有效率为 5 7 7%。5例治疗后行二期手术。 6个月、1、2年生存率分别为 92 36 %、88 5 %、4 6 15 %。中位生存期 14个月。无局部并发症 ,治疗前后肝肾功能和血常规无变化。结论　电化学治疗肝癌是一种简单、安全和有效的新方法 ,副作用少 ,适应证广 Objective To investigate the efficacy and side effects of electrochemical treatment of liver cancer. Methods Twenty-six patients with hepatocellular carcinoma underwent B-guided electrochemical therapy before and after treatment. The clinical manifestations, tumor size, AFP level, histopathology, immune parameters, liver and kidney function and blood routine Variety. Results After treatment, clinical symptoms were relieved, AFP level decreased, and cellular immune function was enhanced. Tissue showed that the treatment area tumor tissue completely or partially necrosis, fibrosis. There were 2 cases of complete remission (CR), 13 partial remission (PR), 2 cases of remission (MR), 7 cases of stable (SD) and 2 cases of progression (PD). The total effective rate was 57.7%. Five patients underwent second-stage surgery. The 6-month, 1-year and 2-year survival rates were 92 36%, 88 5% and 46 6% respectively. The median survival of 14 months. No local complications, liver and kidney function and blood before and after no change. Conclusion Electrochemical treatment of liver cancer is a simple, safe and effective new method with few side effects and wide indications