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探讨碘纺纱条对宫颈锥切术后创面感染的治疗和预防作用。分析我院选取2014年1月-2015年12月我院就诊行宫颈锥形切除术患者30例,宫颈锥切术后阴道内填塞4%的碘仿纱条,术后定期采集宫颈创面周围组织,定量检测肿瘤坏死因子-α(TNF-α)、白细胞介素-6(IL-6)、高迁移率族蛋白1(HMGB1)的表达;同时观察术后1、2、3周阴道分泌物有无异味、宫颈创面有无脓苔,并检测分泌物清洁度,以同期行宫颈锥形切除无碘仿处理的患者30例为对照,进行统计分析。碘纺处理组炎症因子表达低于对照组,差异有统计学意义(P<0.005);碘纺处理组患者阴道及宫颈创面感染率低于对照组,差异有统计学意义(P<0.005)。宫颈锥切术后第1-2周时宫颈创面炎症最为严重,碘纺纱条对宫颈锥切术后创面感染有治疗和预防作用。
To investigate the therapeutic and preventive effects of iodized spinning yarn on wound infection after cervical conization. Analysis of our hospital selected January 2014 - December 2015 in our hospital 30 patients with conization of the cervix, cervix conectomy vaginal stuffing 4% iodoform gauze, after the acquisition of cervical tissue around the organization The levels of tumor necrosis factor-α (TNF-α), interleukin-6 (IL-6) and high mobility group box 1 (HMGB1) were detected by quantitative real- With or without the smell, with or without pus moss in the cervical wound, and to test the secretions’ cleanness. Thirty patients with cervical conical resection without iodoform in the same period were taken as control, and statistical analysis was made. The expression of inflammatory cytokines in the iodinated cotton group was lower than that in the control group (P <0.005). The infection rate of vaginal and cervical wounds in the iodinated cotton group was lower than that in the control group (P <0.005). Cervical conization after 1-2 weeks when the most serious inflammatory wounds, cervical iodine yarn on the wound infection after conization of the cervix have the role of treatment and prevention.