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多年来对肛管齿线附近的侵润性鳞状细胞癌一直采用腹会阴联合切除术,5年生存率为35～68%。近年报道一般在60%左右。新近一组单纯行腹会阴联合切除术后5年和10年生存率分别为62%和52%。第一次世界大战后Gordon-Watson,Gabriel等把放射治疗列为肛管鳞状细胞癌的主要方法,据称效果良好,但并发症严重。随着先进仪器的发展和技术的提高,放疗在肛管癌治疗中的地位又受到重视。Papillon一直是放疗的倡导者,Dalby等亦主张肛管癌宜首选放疗。作者自1972年初开始对肛管癌患者实行术前放疗加化疗,使病灶缩小进而手术根治。作者认为附加
For many years, invasive squamous cell carcinoma near the anal canal line has been treated with abdominal perineal resection. The 5-year survival rate is 35 to 68%. In recent years, the report is generally about 60%. The 5-year and 10-year survival rates after a new group of simple abdominal perineal resection were 62% and 52%, respectively. After World War I, Gordon-Watson, Gabriel et al listed radiation therapy as the main method for squamous cell carcinoma of the anal canal. Allegedly the effect was good but the complications were serious. With the development of advanced instruments and the improvement of technology, the status of radiotherapy in the treatment of anal canal cancer has received attention. Papillon has always been an advocate of radiotherapy. Dalby also advocates that radiotherapy should be the first choice for anal canal cancer. Since the beginning of 1972, the authors began to perform preoperative radiotherapy and chemotherapy for patients with anal canal cancer to reduce the size of the lesion and proceed with radical surgery. Author believes that additional