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目的分析依那普利叶酸片治疗H型高血压的临床效果及其作用机制。方法选取2016年1月-2016年6月医院收治的H型高血压患者120例作为研究对象,根据随机原则分为观察组和对照组各60例,对照组给予依那普利治疗,观察组给予依那普利叶酸片治疗,比较2组患者治疗前后血压、瘦素、血浆同型半胱氨酸(Hcy)水平及左心室质量指数(LVMI)水平。结果治疗前2组血压、瘦素、血浆Hcy和LVMI比较差异无统计学意义(P>0.05),治疗后2组血压水平、瘦素、血浆Hcy及LVMI水平均有所改善,且观察组优于对照组,差异均有统计学意义(P<0.05)。结论依那普利叶酸片治疗H型高血压患者有较好的临床治疗效果,能有效改善患者各项水平值,值得临床推广应用。
Objective To analyze the clinical effect and mechanism of enalapril folate tablets in treating Hypertension. Methods From January 2016 to June 2016, 120 H-type hypertension patients admitted to the hospital were selected as research objects. According to the randomized principle, 60 cases were divided into observation group and control group, and the control group was given enalapril. The observation group The patients were given enalapril folate tablets, and the blood pressure, leptin, plasma homocysteine (Hcy) and left ventricular mass index (LVMI) were compared between the two groups before and after treatment. Results There was no significant difference in blood pressure, leptin, plasma Hcy and LVMI between the two groups before treatment (P> 0.05). After treatment, the levels of blood pressure, leptin, plasma Hcy and LVMI were improved in both groups In the control group, the differences were statistically significant (P <0.05). Conclusion Enalapril folate tablets have a good clinical effect in treating patients with Hypertension, which can effectively improve various levels of patients and is worthy of clinical application.