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癌胚抗原(简称CEA)由Gold和Frcdman首先于1965年从结肠腺癌和胎儿结肠粘膜组织浸液中分离出来.近二十年的研究发现多种肿瘤病人血中CEA明显增高,并与肿瘤的面积,预后及治疗效果有关。但肝、胆疾患时循环中CEA亦可明显增加.肝脏在调节CEA中有重要作用。CEA是一种分子量为200,000的糖蛋白,糖含量为55～65%.糖链终未多为岩藻糖或唾液酸亦可为半乳糖和N-乙酰萄糖胺。CEA的结构与其代谢关系
Carcinoembryonic antigen (CEA) was first isolated from colon adenocarcinoma and fetal colonic mucosa by Gold and Frcdman in 1965. Nearly two decades of studies have shown that CEA in blood of various tumor patients is significantly higher than that of tumor Area, prognosis and treatment effect. However, liver and gallbladder disease CEA cycle can be significantly increased.Liver in the regulation of CEA has an important role. CEA is a glycoprotein with a molecular weight of 200,000 with a sugar content of 55-65%, and no more fucose or sialic acid at the end of the sugar chain can also be galactose and N-acetylglucosamine. The structure of CEA and its metabolic relationship