近年来,人们甚为重视细胞表面成分在肿瘤形成过程中的变化。许多文章报道肿瘤细胞膜的组成、结构、功能与正常者有明显的差别。 哺乳动物的肝凝集素(HL)也是一种细胞膜成分。它专一性地与末端为β-半乳糖苷的糖蛋白及糖脂结合。在体内它介导许多去唾液酸糖蛋白的内香,然后在肝细胞内降解。肝凝集素也可能参与肝细胞间的粘着,并与肿瘤肝转移的形成相关。 In recent years, people have attached great importance to the changes of cell surface components in the process of tumor formation. Many articles have reported that the composition, structure and function of tumor cell membranes are significantly different from those of normal people. The mammalian hemagglutinin (HL) is also a cell membrane component. It specifically binds to β-galactoside-containing glycoproteins and glycolipids. In vivo it mediates the endosiam of many asialoglycoproteins and then degrades in hepatocytes. Hemagglutinin may also be involved in adhesion between hepatocytes and is associated with the formation of liver metastases.