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以前曾报告过一些肺的非鳞状,无粘液分泌的上皮性肿瘤,对表面活性物质载脂蛋白(Surfactantapoprotein,SA)具有免疫反应性,说明其系来自肺泡Ⅱ型细胞或向肺泡的Ⅱ型肺细胞分化.电镜图像和免疫过氧化酶染色显示,SA 的特异性可作为Ⅱ型肺细胞肿瘤的一种标记.在Ⅱ型肺细胞肿瘤中,SA作为核包含体而存在。从过去观察中发现,肿瘤有 SA 者,预后似乎较好.为此,作者报告一组 SA 阳性的Ⅱ型肺细胞癌的临床病理研究,并和组织学相似而SA 阴性的肿瘤作了比较。
Previously, some non-squamous, non-mucinous epithelial tumors of the lung have been reported to be immunoreactive with the surfactant apolipoprotein (SA), indicating that they are derived from alveolar type II cells or type II into the alveoli. Pulmonary cell differentiation. Electron microscopy images and immunoperoxidase staining showed that the specificity of SA can be used as a marker for type II pneumocyte tumors. In type II pneumocytic tumors, SA exists as a nuclear inclusion body. It has been observed from past observations that tumors with SA have a better prognosis. For this reason, the authors reported a clinicopathological study of a group of SA-positive type II pneumocytic carcinomas and compared them with histologically similar and SA-negative tumors.