论文部分内容阅读
目的探讨前哨淋巴结活检(SLNB)并保乳治疗早期乳腺癌的临床疗效及体会。方法选取中山市人民医院2009年1月-2015年12月90例行SLNB并保乳治疗的早期乳腺癌患者作为观察组并进行回顾性分析,选取同一时间基本资料相匹配进行腋窝淋巴结清扫(ALND)的30例患者作为对照组。对比两组患者的手术时间、手术出血量及拔管时间等。结果 SLNB组与ALND组手术时间分别为(51.70±8.60)min和(92.90±17.30)min,术中出血量分别为(30.90±6.60)ml和(100.80±20.20)ml,拔管时间分别为(5.50±1.30)d和(14.10±3.50)d,差异均有统计学意义(P<0.05);SLNB组治疗后患者生活质量评分均明显高于对照组;SLNB组与ALND组并发症比较,ALND组发生5例上肢水肿、15例活动受限以及30例感觉异常;SLNB组未发生上肢水肿和活动受限,发生30例感觉异常。结论 SLNB并保乳治疗早期乳腺癌的疗效满意,并发症少,具有重要的临床应用价值。
Objective To investigate the clinical efficacy and experience of sentinel lymph node biopsy (SLNB) and breast-conserving treatment of early-stage breast cancer. Methods 90 patients with early breast cancer treated by SLNB and breast-conserving therapy in Zhongshan People’s Hospital from January 2009 to December 2015 were selected as the observation group and retrospectively analyzed. The basic data at the same time were matched for axillary lymph node dissection (ALND ) Of 30 patients as a control group. Comparing the two groups of patients surgery time, surgical bleeding and extubation time. Results The operative time of SLNB group and ALND group was (51.70 ± 8.60) min and (92.90 ± 17.30) min respectively, and the intraoperative blood loss was (30.90 ± 6.60) ml and (100.80 ± 20.20) ml respectively. The extubation time was 5.50 ± 1.30) d and (14.10 ± 3.50) d respectively, the differences were statistically significant (P <0.05). The quality of life of patients in SLNB group was significantly higher than that in control group. Comparing the complications of SLNB group and ALND group, ALND There were 5 cases of upper extremity edema, 15 cases of limited activity and 30 cases of sensory abnormalities. There was no upper extremity edema and limited activity in SLNB group, and 30 cases of sensory abnormalities occurred. Conclusion SLNB breast-conserving treatment of early breast cancer with satisfactory results, fewer complications, has important clinical value.