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甲硝唑又称灭滴灵,具有杀灭滴虫、阿米巴原虫及抗厌氧菌作用已为人们所熟悉。但用于治疗非厌氧菌感染文献报告很少。我们于1989年1～10月,应用甲硝唑治疗新生儿败血症30例,效果满意,现报告如下。临床资料男19例,女11例,足月新生儿28例,早产儿2例。母乳喂养22例,人工喂养5例,混合喂养2例,尚未开奶1例。其中28例来自农村。症状与体征:体温不升1例,发热29例,拒乳和吮乳减少15例,精神不振13例。黄疸8例,抽搐4例,皮肤硬肿及面色发绀各2例,口吐泡沫1例,脐部有脓性分泌物8例。
Metronidazole, also known as metronidazole, has the effect of killing trichomoniasis, amoeba and anti-anaerobic bacteria has been well-known. However, few reports have been reported on the treatment of non-anaerobic infections. We from January 1989 to October, the application of metronidazole treatment of neonatal sepsis in 30 cases, the results are satisfactory, are as follows. Clinical data of 19 males and 11 females, 28 full-term newborns, 2 premature children. Breastfeeding in 22 cases, artificial feeding in 5 cases, mixed feeding in 2 cases, yet to open milk in 1 case. 28 of them came from rural areas. Symptoms and signs: 1 case of body temperature does not rise, fever in 29 cases, 15 cases of refusal to milk and sucking milk, 13 cases of lack of energy. 8 cases of jaundice, convulsions in 4 cases, 2 cases of skin edema and cyanosis in each case, 1 case of foaming on the mouth, purulent umbilical secretions in 8 cases.