我科近三十年收治恶性胸膜间皮瘤12例，报告如下。一、一般资料12例中，男8例，女4例，年龄18～64岁。12例患者均以胸痛为首发症状，胸痛呈进行性加重，胸液出现后症状无缓解，病程平均8个月。X线表现为胸膜不规则增厚5例，纵隔肿块2例。突向胸膜腔块影4例，肺野内多发块影伴胸 Our department has treated 12 cases of malignant pleural mesothelioma in the past 30 years. The report is as follows. First, general information 12 cases, 8 males and 4 females, aged 18 to 64 years old. All the 12 patients had chest pain as the first symptom, and chest pain was progressively aggravated. There was no remission of symptoms after pleural fluid appeared. The average duration was 8 months. X-ray showed irregular pleural thickening in 5 cases, mediastinal mass in 2 cases. There were 4 sudden pleural cavity shadows and multiple chest shadows in the lung field.