目的　探讨经皮细针肺肿块吸取细胞块和微小碎片组织学 (简称微小切片 )与涂片细胞学的诊断价值。方法　对有组织学对比的 187例经皮细针 (7号 )肺部肿块吸取资料作微小切片组织学与涂片细胞学比较分析。结果　 (1)微小切片组的诊断敏感性 88 3% ,特异性 10 0 % ,总准确率89 5 % ;涂片组分别为 87 7%、93 8%和 88 8% ;涂片结合微小切片则分别为 91 6 %、93 8%和 92 0 %。(2 )微小切片组对恶性肿瘤的组织分型准确率 93 3% (83/ 89) ,比涂片组的 6 7 9% (91/ 134 )高 (P <0 0 1)。对良性病变分类诊断准确率分别为 86 4% (19/ 2 2 )和 6 0 0 % (18/ 30 ) (P <0 0 5 )。 (3) 6 6 3%的病例获取微小组织切片 ,其免疫组织化学染色结果与术后病理组织切片的相同。结论　微小切片组织学和细胞学的诊断准确性均高 ,两者结合应用将提高诊断准确性 ,前者对组织分型、分类诊断接近术后病理诊断 ,有很高的应用价值 Objective To investigate the diagnostic value of histopathology (abbreviated as microsection) and smeg cytology for aspiration of cell mass and microsection in percutaneous fine needle lung lumps. Methods 187 cases of histologically-matched percutaneous fine needle (No.7) lung mass were taken for comparison of histology and smear cytology. Results: (1) The diagnostic sensitivity of micro-slice group was 88.3%, specificity was 100%, total accuracy was 89.5%; smear group was 87.7%, 93.8% and 88.8% respectively; smear combined with micro-section Then 91 6%, 93 8% and 92 0% respectively. (2) The accuracy rate of tissue typing in malignant tumor was 93 3% (83/89) in microsection group, which was higher than that of smear group (69/13%) (P 0 01). The diagnostic accuracy for the classification of benign lesions were 86 4% (19/2 2) and 600% (18/30), respectively (P 0 05). (3) Sixty-three percent of the cases were obtained microscopic sections, and the immunohistochemical staining results were the same as those of postoperative pathological sections. Conclusion The diagnostic accuracy of micro-section histology and cytology are high, the combination of the two will improve the diagnostic accuracy, the former of the tissue classification, classification diagnosis close to postoperative pathological diagnosis, has a high value