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为了解微量元素锌在镉性肾损伤中的作用，在给大鼠腹腔注射镉（ＣｄＣｌ２１５μｍｏｌ／ｋｇ）与巯基乙醇（ＭＥ３００μｍｏｌ／ｋｇ）混合液的同时及２小时后，皮下注射锌（ＺｎＳＯ４１５μｍｏｌ／ｋｇ）。结果显示：加锌可使镉所降低的线粒体锌恢复至正常水平，使被镉降低的线粒体超氧化物歧化酶（ＳＯＤ）活力有所恢复，并使胞核内镉的转移速率加快，同时受损的肾功能及超微结构得到一定程度的改善。提示锌在镉性肾损伤的防护中可能具有一定价值
To understand the role of trace element zinc in cadmium-induced renal injury, zinc (ZnSO4 15 μmol / kg) was subcutaneously injected into rats intraperitoneally with a mixture of cadmium (CdCl2 15 μmol / kg) and mercaptoethanol (ME300 μmol / ). The results showed that adding zinc could restore the mitochondrial zinc reduced by cadmium to normal levels, restore the mitochondrial superoxide dismutase (SOD) activity reduced by cadmium, and accelerate the transfer rate of cadmium in the nucleus Damage to renal function and ultrastructure to some extent improved. Tip zinc in the protection of cadmium kidney damage may have some value