本文选用荧光偏振免疫分析方法,测试了8名健康志愿受试者,单剂量肌注庆大霉素80mg 后的血药浓度经时过程,用微机MCPKP 药物动力学程序处理并求得庆大霉素的药物动力学参数、吸收速率常数(Ka)、消除速率常数(K)、消除半衰期(T_(1/2)k)、表观分布容积(Vd)、达峰时间(Tp)等,与文献报告值接近,可作给药剂量估算的依据. In this paper, fluorescence polarization immunoassay method was used to test the eight healthy volunteers, single-dose intramuscular injection of gentamicin 80mg after the blood concentration over time, with the computer MCPKP pharmacokinetic program and get Gentamicin (Ka), elimination rate constant (K), elimination half-life (T 1/2) k, apparent volume of distribution (Vd), peak time (Tp) Reported values ​​close to the literature, can be used as a basis for dose estimates.